This study provides an overview of the clinical applications of neurofeedback, encompassing various treatment protocols and system designs involving Brain-Computer Interface (BCI) and Virtual Reality (VR) technology. Neurofeedback typically involves recording EEG, extracting various brain activity components, and providing feedback to subjects, allowing them to monitor changes during training and assess their progress for optimal performance. Specific electrode placement based on brain functions and symptoms simplifies the treatment process. Commonly used protocols include alpha, beta, theta, and alpha/theta protocols.